as in clinical depression, a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies
Gray JP, Müller VI, Eickhoff SB, Fox PT. Multimodal Abnormalities of Brain Structure and Function in Major Depressive Disorder: A Meta-Analysis of Neuroimaging Studies. American Journal of Psychiatry. Feb 2020. [anima] [pubmed] [doi]
The BrainMap project is funded by the National Institutes of Health / National Institute of Mental Health award numberĀ 5R01MH074457-15.